Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced apoptosis of B and T lymphocytes in TAFII105 dominant-negative transgenic mice is linked to nuclear factor-kappa B.

The Journal of biological chemistry - 17 May 2002

Silkov Antonina, Wolstein Orit, Shachar Idit, Dikstein Rivka

Abstract excerpt

The general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 12-14 TBP-associated factors (TAF(II)s). Some TAF(II)s act as bridges between transcription activators and the general transcription machinery through direct interaction with activation domains. Although TAF-mediated transcription activation has been established, there is little genetic evidence connecting it to binding of an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to B-Lymphocytes
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NF-kappa B

Share to T-Lymphocytes

Share to TATA-Binding Protein Associated Factors

Share to Transcription Factor RelA

Share to Transcription Factor TFIID

Source

Identifiers

PMID: 11856754
DOI: 10.1074/jbc.M200696200

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced apoptosis of B and T lymphocytes in TAFII105 dominant-negative transgenic mice is linked to nuclear factor-kappa B.PMID 11856754Read ↗

TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB.Semantic proximity Read ↗

NF-κB1 p105 Regulates T Cell Homeostasis and Prevents Chronic InflammationSemantic proximity Read ↗

TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS.Semantic proximity Read ↗

Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice.Semantic proximity Read ↗

DT40 mutants: a model to study transcriptional regulation of B cell development and function.Semantic proximity Read ↗

TGF-β type II receptor–deficient thymocytes develop normally but demonstrate increased CD8+ proliferation in vivoSemantic proximity Read ↗

A role for FADD in T cell activation and development.Semantic proximity Read ↗

Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model.Semantic proximity Read ↗

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.Semantic proximity Read ↗

Requirement for efficient interactions between CD4 and MHC class II molecules for survival of resting CD4+ T lymphocytes in vivo and for activation-induced cell death.Semantic proximity Read ↗

Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation.Semantic proximity Read ↗

B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.