Article
Identification and characterization of pro-T lymphocytes and lineage-uncommitted lymphocyte precursors from mice with three novel surface markers.
The Journal of experimental medicine - 1 Jul 1990
Palacios R, Samaridis J, Thorpe D, Leu T
Abstract excerpt
The study of prethymic stages of T cell development has been limited because specific markers for mouse pro-T lymphocytes were not available. We developed a panel of rat monoclonal antibodies (mAbs) that bind to our pro-T lymphocyte clones obtained from bone marrow of young adult mice and the thy...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Surface
- Bone Marrow Cells
- Cell Differentiation
- Cell Line
- Cell Separation
- Female
- Flow Cytometry
- Hematopoietic Stem Cells
- Hybridomas
- Immunoenzyme Techniques
- Liver
- Lymphokines
- Mice
- Mice, Mutant Strains
- Phenotype
- Rats