Article
A requirement for CARMA1 in TCR-induced NF-kappa B activation.
Nature immunology - 1 Sept 2002
Wang Donghai, You Yun, Case Sara M, McAllister-Lucas Linda M, Wang Lin, DiStefano Peter S, Nuñez Gabriel, Bertin John, Lin Xin
Abstract excerpt
Stimulation of the T cell receptor (TCR) complex initiates multiple signaling cascades that lead to the activation of several transcription factors, including the NF-kappa B family members. Although various proximal signaling components of the TCR have been intensively studied, the distal compone...
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