Article
CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB.
Molecular immunology - 1 Jul 2011
Oruganti Sreenivasa Rao, Edin Sofia, Grundström Christine, Grundström Thomas
Abstract excerpt
Recognition of antigen by T- or B-cell receptors leads to formation of an immunological synapse and initiation of signalling events that collaborate to determine the nature of the adaptive immune response. Activation of NF-κB transcription factors has a key role in regulation of numerous genes with important functions in immune responses and inflammation and is of great importance for lymphocyte activation and...
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