Article
Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production.
Molecular immunology - 1 May 2014
Cheng Jing, Hamilton Kristia S, Kane Lawrence P
Abstract excerpt
Previous studies from our group and others have shown that the Akt kinase can contribute to induction of NF-κB by antigen receptor signaling. However, the direct targets of Akt in this pathway are not known. Here we show that Akt-mediated NF-κB activation is mediated at least in part through dire...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
