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Article

T-cell receptor signaling induces proximal Runx1 transactivation via a calcineurin-NFAT pathway.

European journal of immunology - 1 Mar 2014

Wong Won Fen, Looi Chung Yeng, Kon Shunsuke, Movahed Elaheh, Funaki Tomo, Chang Li Yen, Satake Masanobu, Kohu Kazuyoshi

Abstract excerpt

Runx1 transcription factor is a key player in the development and function of T cells. Runx1 transcripts consist of two closely related isoforms (proximal and distal Runx1) whose expressions are regulated by different promoters. Which Runx1 isoform is expressed appears to be tightly regulated. Th...

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Source

Identifiers

PMID: 24310293
DOI: 10.1002/eji.201343496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24310293-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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