Article
Upstream open reading frames regulate the translation of the multiple mRNA variants of the estrogen receptor alpha.
The Journal of biological chemistry - 4 Oct 2002
Kos Martin, Denger Stefanie, Reid George, Gannon Frank
Abstract excerpt
It is by now well established that the estrogen receptor alpha (ER alpha) is transcribed from multiple promoters. One direct consequence of multiple promoters is the generation of mRNA variants with different 5'-untranslated regions (5'-UTRs). However, the potential roles of these individual mRNA variants are not known. All 5'-UTRs of ER alpha contain between one and six upstream open reading frames. In this...
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