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Article

p130 mediates TGF-beta-induced cell-cycle arrest in Rb mutant HT-3 cells.

Gynecologic oncology - 1 Aug 2002

Choi Hyun Ho, Jong Hyun Soon, Hyun Song Sang, You Kim Tae, Kyeong Kim Noe, Bang Yung Jue

Abstract excerpt

OBJECTIVE: The retinoblastoma proteins include Rb and the functionally and structurally related proteins p107 and p130. It has been reported that HT-3 cells are sensitive to TGF-beta growth inhibition, despite the Rb mutation. The purpose of this study was to elucidate the growth-inhibitory mechanism of TGF-beta in Rb mutant HT-3 cells. METHODS: Growth inhibition by TGF-beta in cervical carcinoma cell lines was...

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Source

Identifiers

PMID: 12144826
DOI: 10.1006/gyno.2002.6740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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