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Article

CTGF modulates cell cycle progression in cAMP-arrested NRK fibroblasts

1 Jan 2000

Abstract excerpt

Connective tissue growth factor (CTGF) is a 38-kDa cysteine-rich peptide, whose synthesis and secretion are selectively induced by transforming growth factor beta (TGF-beta) in connective tissue cells. Previous studies have demonstrated that CTGF functions as a downstream mediator of TGF-beta mitogenic activity, where it controls cell cycle progression through late G1 and S-phase entry of NRK fibroblast...

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PMID: 10567923
DOI: 10.1002/(sici)1097-4652(200001)182:1<119::aid-jcp13>3.0.co;2-4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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