Article
CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm.
Gynecologic oncology - 1 Aug 2002
Aktas Dilek, Guney Inci, Alikasifoglu Mehmet, Yüce Kunter, Tuncbilek Ergul, Ayhan Ali
Abstract excerpt
OBJECTIVE: Gene-environment interactions have been the focus of a number of recent studies of the occurrence of human cancers, and an association between the risk and the CYP1A1*3 polymorphism has been noticed for several cancers. Previous studies suggest that estrogens are involved in the etiology of ovarian cancer. The cytochrome P450 1A1 (CYP1A1) gene polymorphism may play role in the development of epithelial...
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