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Article

Importance of CYP1A1 polymorphism and its transcriptional regulation in ovarian and endometrial cancer.

Ginekologia polska - 1 Dec 2011

Mrozikiewicz Przemysław M, Grześkowiak Edmund, Seremak-Mrozikiewicz Agnieszka, Bogacz Anna, Barlik Magdalena, Semczuk Andrzej, Bartkowiak-Wieczorek Joann, Drews Krzysztof

Abstract excerpt

Human cytochrome P450 1A 1 is one of the most important enzymes participating in human carcinogenesis because it metabolites several procarcinogens to active carcinogenic metabolites. Additionally enzymes of CYP450 family play an important role in estrogenes catabolization (17-beta-estradiol and estron) to intermediate products (2-, 4-hydroxyestradiol and 2-, 4-hydroxyestrone) including CYP1A1 that catalyses...

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PMID: 22384629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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