Polymorphisms related to estrogen and xenobiotic metabolism in healthy Turkish women.

doi:10.1016/j.arcmed.2004.10.003

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Article

Polymorphisms related to estrogen and xenobiotic metabolism in healthy Turkish women.

Archives of medical research - 1 Jan 2000

Kocabaş Neslihan Aygün, Sardaş Semra, Sardas Semra, Karakaya Ali Esat, Karakaya Ali Estat

Abstract excerpt

BACKGROUND: Polymorphisms which are inherited alterations in the activity of cytochrome P450 1B1 (CYP1B1), catechol O-methyltransferase (COMT), manganese superoxide dismutase (MnSOD) hold the potential to define differences in estrogen metabolism and, thereby, possibly explain inter-individual differences in cancer susceptibility associated with estrogen-mediated carcinogenesis. METHODS: The CYP1B1 (L432V), COMT...

Topics

Adult
Aryl Hydrocarbon Hydroxylases
Catechol O-Methyltransferase
Cytochrome P-450 CYP1B1
Cytochrome P-450 Enzyme System
Estrogens
Female
Genetic Predisposition to Disease
Genotype
Humans
Middle Aged
Polymorphism, Genetic
Superoxide Dismutase
Turkey
Xenobiotics

Source

Open in PubMed

Identifiers

PMID: 15777990
DOI: 10.1016/j.arcmed.2004.10.003

Genes

COMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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