Article
Interaction between CYP1A1 polymorphic variants and dietary exposures influencing ovarian cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2003
Terry Kathryn L, Titus-Ernstoff Linda, Garner Elizabeth O, Vitonis Allison F, Cramer Daniel W
Abstract excerpt
Aromatic hydrocarbon hydroxylase (CYP1A1) is involved in the metabolism of many substrates and the subject of cancer studies. This study examined the association between two polymorphic variants of CYP1A1 and ovarian cancer risk. The frequencies of the Msp1 and Ile/Val variants of CYP1A1 were determined in 445 ovarian cancer cases and 472 general population controls in New England. Overall relative risks were...
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