Article
Comparative analysis of SNP in estrogen-metabolizing enzymes for ovarian, endometrial, and breast cancers in Novosibirsk, Russia.
Advances in experimental medicine and biology - 1 Jan 2008
Gulyaeva Lyudmila F, Mikhailova Olga N, PustyInyak Vladimir O, Kim Inessa V, Gerasimov Alexei V, Krasilnikov Sergey E, Filipenko Maxim L, Pechkovsky Eugene V
Abstract excerpt
We estimated the frequency of CYP1A1, CYP1A2, CYP1B1, CYP19, and SULT1A1 allelic variants in a female population of the Novosibirsk district and their association with the elevated risk of breast (BC), ovarian (OC), and endometrial (EC) cancers. Significant differences (OR = 2.34, p = 0.0002) in the allele distributions for CYP1A1 M1 polymorphism between patients with BC (n = 118) and controls (n = 180) were...
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