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Article

Cytochrome P450 1A1 Ile462Val polymorphism and oral carcinoma risk: an updated meta-analysis including 1,515 cases and 2,233 controls.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2012

Zhuo Xianlu, Zhao Houyu, Chang Aoshuang, Ye Huiping, Zhou Yan, Song Yufeng, Tan Yinghui

Abstract excerpt

Cytochrome P450 (CYP) 1A1 Ile462Val (exon7) polymorphism has been suggested to be a risk factor for several cancers. Published data on its association with oral cancer risk have generated conflicting results. Our previous meta-analysis containing data from prior to Jan 2008 regarding this issue failed to find a significant association between CYP1A1 Ile462Val variation and oral cancer susceptibility. An updated...

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PMID: 22847262
DOI: 10.1007/s13277-012-0467-3

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