Article
CYP1A1 gene polymorphism and risk of endometrial hyperplasia and endometrial carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000
Esinler I, Aktas D, Alikasifoglu M, Tuncbilek E, Ayhan A
Abstract excerpt
The cytochrome P4501A1 (CYP1A1) is involved in the metabolism of environmental carcinogens and estrogen. We hypothesized that CYP1A1 genetic polymorphism may be a susceptibility factor for endometrial hyperplasia (EH) and endometrial carcinoma (ECa). We therefore evaluated this hypothesis in patients with EH and ECa and control subjects using allele-specific polymerase chain reaction-based method in a Turkish...
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