Article
Functional expression of human methionine aminopeptidase type 1 in Saccharomyces cerevisiae.
Protein and peptide letters - 1 Aug 2002
Dummitt Benjamin, Fei Ying, Chang Yie-Hwa
Abstract excerpt
We expressed recombinant human methionine aminopeptidase type 1 (MAP or MetAP) in a map1 null yeast strain to determine the extent of functional complementation between the two proteins. The human MetAP1 protein fully rescued the slow growth phenotype associated with deletion of yeast MetAP1, suggesting that the yeast and human MetAP1 proteins may have similar roles in vivo. Expression of human MetAP1 in yeast...
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