Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases.

doi:10.1073/pnas.92.26.12357

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Article

Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases.

Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 1995

Li X, Chang Y H

Abstract excerpt

We previously characterized a methionine aminopeptidase (EC 3.4.11.18; Met-AP1; also called peptidase M) in Saccharomyces cerevisiae, which differs from its prokaryotic homologues in that it (i) contains an N-terminal zinc-finger domain and (ii) does not produce lethality when disrupted, although...

Topics

Amino Acid Sequence
Aminopeptidases
Animals
Base Sequence
Cloning, Molecular
DNA Primers
Escherichia coli
Gene Deletion
Gene Expression
Gene Library
Genes, Fungal
Genes, Lethal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Suppressor

Humans

Kinetics

Methionyl Aminopeptidases

Molecular Sequence Data

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 8618900
DOI: 10.1073/pnas.92.26.12357
PMCID: PMC40356

Genes

MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8618900-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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