Article
Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombe.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 1997
Colussi P A, Taron C H, Mack J C, Orlean P
Abstract excerpt
Dolichol phosphate mannose (Dol-P-Man), formed upon transfer of Man from GDPMan to Dol-P, is a mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of protein. Dol-P-Man synthase is an essential protein in Saccharomyces cerev...
Topics
- Amino Acid Sequence
- Animals
- Genes, Fungal
- Genes, Lethal
- Genetic Complementation Test
- Humans
- Mannosyltransferases
- Molecular Sequence Data
- Mutation
- Rats
- Saccharomyces cerevisiae
- Schizosaccharomyces
- Sequence Homology, Amino Acid