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Article

Single point mutations in Met4p impair the transcriptional repression of MET genes in Saccharomyces cerevisiae.

FEBS letters - 3 Jun 1996

Omura F, Fujita A, Shibano Y

Abstract excerpt

Transcription of MET genes in Saccharomyces cerevisiae depends on a transcriptional activator, the MET4 gene product (Met4p). Using in vitro mutagenesis, we isolated two mutant MET4 alleles encoding [Pro215]Met4p and [Ser156]Met4p. These mutations impeded Met4p's responsiveness to methionine in the media, and yeast cells carrying mutant alleles exhibited enhanced transcription of MET genes under repressing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8674545
DOI: 10.1016/0014-5793(96)00486-3

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Single point mutations in Met4p impair the transcriptional repression of MET genes in Saccharomyces cerevisiae.PMID 8674545Read ↗

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