Article
Association of Q551R polymorphism in the interleukin 4 receptor gene with nonatopic asthma in Slovenian children.
Wiener klinische Wochenschrift - 1 May 2010
Berce Vojko, Potocnik Uros
Abstract excerpt
BACKGROUND: Asthma is one of the most common chronic diseases of childhood and results from the interaction of several genes and environmental influences. Interleukin 4 (IL4) and its receptor IL4R have a central role in the regulation of immunoglobulin E (IgE) production and thereby in the induction and maintenance of allergy and asthma. The single nucleotide polymorphisms (SNPs) Q551R in the IL4RA gene and C-33T...
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