Article
Association analysis of interleukin 5 receptor alpha subunit (IL5RA) polymorphisms and asthma.
Journal of human genetics - 1 Jan 2005
Cheong Hyun Sub, Kim Lyoung Hyo, Park Byung Lae, Choi Yoo Hyun, Park Hae-Sim, Hong Soo-Jong, Choi Byoung Whui, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
The alpha subunit of interleukin 5 receptor (IL5RA) on chromosome 3p26-p24 is known to regulate the development and function of eosinophils. In an effort to discover additional polymorphism(s) in genes whose variant(s) have been implicated in asthma, we investigated the genetic polymorphisms in IL5RA to evaluate the gene as a potential candidate for a host genetic study of asthma. By direct DNA sequencing in 24...
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