Article
Enzymatic properties of a new peptide deformylase from pathogenic bacterium Leptospira interrogans.
Biochemical and biophysical research communications - 26 Jul 2002
Li Yikun, Chen Zhifeng, Gong Weimin
Abstract excerpt
Peptide deformylase (LiPDF), a target protein for antibacterial agents from pathogenic bacteria Leptospira interrogans was identified and purified. Enzymatic studies including kinetics and inhibition revealed new inspiring highlights. The purified active enzyme was a dimer and showed a hyperbolic progress plot when the substrate was low but an excess substrate inhibition effect in higher substrate concentration....
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