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Article

Involvement of the non-active site Residues in the Catalytic Activity of NDM-4 Metallo beta-lactamase.

The protein journal - 1 Aug 2023

Verma Jyoti, Jain Diamond, Panda Aditya Prasad, Kant Shri, Kumar Gaurav, Ghosh Anindya Sundar

Abstract excerpt

The rise of New Delhi metallo beta-lactamase (NDM) producing bacteria imposes a significant threat to the treatment of bacterial infections due to their broad spectrum against beta-lactams. The activity of metallo beta-lactamases is affected by active site residues as well as residues near the active site. Therefore, we aimed to identify the amino acid residues around the active site of NDM-4 which influence its...

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Identifiers

PMID: 37170014
DOI: 10.1007/s10930-023-10124-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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