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Article

Dissecting the catalytic and substrate binding activity of a class II lanthipeptide synthetase BovM.

Biochemical and biophysical research communications - 25 Jul 2014

Ma Hongchu, Gao Yong, Zhao Fangyuan, Wang Jian, Teng Kunling, Zhang Jie, Zhong Jin

Abstract excerpt

LanM proteins are the synthetases of the class II lanthipeptides, which are responsible for lanthionine or methyllanthionine formation in lanthipeptides. LanMs are bifunctional enzymes with N-terminal dehydratase and C-terminal cyclase domains. However, the catalytic and especially the substrate binding function of LanM are not fully investigated. In this study, we analyzed the function of conserved residues of...

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PMID: 24998443
DOI: 10.1016/j.bbrc.2014.06.129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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