Article
Association study between two variants in the DOPA decarboxylase gene in bipolar and unipolar affective disorder.
American journal of medical genetics - 8 Jul 2002
Jahnes Esther, Müller Daniel J, Schulze Thomas G, Windemuth Christine, Cichon Sven, Ohlraun Stephanie, Fangerau Heiner, Held Tilo, Maier Wolfgang, Propping Peter, Nöthen Markus M, Rietschel Marcella
Abstract excerpt
Irregularities of dopaminergic and serotonergic neurotransmission have been implicated in a variety of neuropsychiatric disorders. DOPA decarboxylase (DDC), also known as aromatic L-amino acid decarboxylase, is an enzyme involved directly in the synthesis of dopamine and serotonin and indirectly in the synthesis of noradrenaline. Therefore, the DDC gene can be considered as a candidate gene for affective...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.