Article
The dysbindin gene in major depression: an association study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2004
Zill Peter, Baghai Thomas C, Engel Rolf, Zwanzger Peter, Schüle Cornelius, Eser Daniela, Behrens Stefanie, Rupprecht Rainer, Möller Hans-Jürgen, Ackenheil Manfred, Bondy Brigitta
Abstract excerpt
The pathophysiological mechanisms, as well as the molecular loci of antidepressant drug action have not yet been established, but recent models proposed that several adaptive mechanisms in signal transduction cascades beyond the receptor and reuptake systems are involved in antidepressant action and play an important role in the etiology of affective disorders. In this context, the dysbindin gene...
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