Article
No association of a functional polymorphism in the dopamine D2 receptor promoter region with bipolar or unipolar affective disorders.
American journal of medical genetics - 7 Sept 1998
Furlong R A, Coleman T A, Ho L, Rubinsztein J S, Walsh C, Paykel E S, Rubinsztein D C
Abstract excerpt
The dopaminergic system, along with the serotonergic and noradrenergic systems, has been implicated in the etiology of mood disorders. An association study of a functional variant in the promoter region of the dopamine D2 receptor (DRD2) with bipolar affective disorder I or unipolar major affecti...
Topics
- Bipolar Disorder
- Depressive Disorder
- Female
- Genetic Linkage
- Genetic Predisposition to Disease
- Genome, Human
- Humans
- Male
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Receptors, Dopamine D2