Article
Association between dopa decarboxylase gene variants and borderline personality disorder.
Psychiatry research - 30 Nov 2014
Mobascher Arian, Bohus Martin, Dahmen Norbert, Dietl Lydie, Giegling Ina, Jungkunz Martin, Kleindienst Nikolaus, Limberger Matthias, Meisenzahl Eva, Rietschel Marcella, Roepke Stefan, Schmahl Christian, Schott Björn, Schwarze Cornelia E, Tadić André, Treutlein Jens, Vogel Friederike, Witt Stephanie H, Zetzsche Thomas, Rujescu Dan, Lieb Klaus
Abstract excerpt
Despite heritability estimates of 37-69%, research has identified few genetic risk variants for borderline personality disorder (BPD). The present collaborative candidate gene study of 987 BPD cases and 1110 healthy controls found an association between BPD and single nucleotide polymorphism rs12718541 in the dopa decarboxylase gene.
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