Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of DNA repair gene polymorphisms on BPDE-DNA adducts in human lymphocytes.

International journal of cancer - 1 Jul 2002

Pastorelli Roberta, Cerri Annalisa, Mezzetti Maurizio, Consonni Erica, Airoldi Luisa

Abstract excerpt

To determine whether variations in DNA repair genes are related to host DNA damage, we investigated the association between polymorphism in the XPD gene (codon 199, 312, 751) and the XRCC1 gene (codon 194, 399) and the presence of benzo(a)pyrene diolepoxide adducts to lymphocyte DNA (BPDE-DNA) in a group of male patients with incident lung cancer, all current smokers. BPDE-DNA adducts were analyzed by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to DNA Repair
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Proteins

Share to Transcription Factors

Source

Identifiers

PMID: 12115580
DOI: 10.1002/ijc.10463

Genes

XRCC1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of DNA repair gene polymorphisms on BPDE-DNA adducts in human lymphocytes.PMID 12115580Read ↗

Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer.Semantic proximity Read ↗

Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide.Semantic proximity Read ↗

Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer risk.Semantic proximity Read ↗

Genetic polymorphisms in DNA repair genes and risk of lung cancer.Semantic proximity Read ↗

GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels.Semantic proximity Read ↗

Correlation between base-excision repair gene polymorphisms and levels of in-vitro BPDE-induced DNA adducts in cultured peripheral blood lymphocytes.Semantic proximity Read ↗

Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells.Semantic proximity Read ↗

Effect of XPD/ERCC2 polymorphisms on chromosome aberration frequencies in smokers and on sensitivity to the mutagenic tobacco-specific nitrosamine NNK.Semantic proximity Read ↗

The Effect of Polymorphisms in DNA Repair Genes and Carcinogen Metabolizers on Leukocyte Telomere Length: A Cohort of Healthy Spanish Smokers.Semantic proximity Read ↗

Polymorphisms of DNA repair genes and lung cancer in chromium exposure.Semantic proximity Read ↗

ERCC2 /XPD gene polymorphisms and lung cancer: a HuGE review.Semantic proximity Read ↗

Influence of DNA repair polymorphisms on biomarkers of genotoxic damage in peripheral lymphocytes of healthy subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.