Article
Polymorphisms of DNA repair genes and lung cancer in chromium exposure.
Advances in experimental medicine and biology - 1 Jan 2015
Sarlinova M, Majerova L, Matakova T, Musak L, Slovakova P, Skereňová M, Kavcová E, Halašová E
Abstract excerpt
Chromium is a well known carcinogen involved in the lung cancer development. Polymorphism of some of the DNA repair genes may be associated with elevated risk of cancerous transformation. In the present study, we investigated the polymorphisms of the following selected members of the base and nucleotide excision repair genes: XPC (Lys939Gln), XPD (Lys751Gln), XRCC1(Arg399Gln), and hOGG1(Ser326Ser), and the risk...
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