Article
Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer.
Environmental and molecular mutagenesis - 1 Jan 2004
Harms Carsten, Salama Salama A, Sierra-Torres Carlos H, Cajas-Salazar Nohelia, Au William W
Abstract excerpt
We have previously investigated the role of polymorphic chemical metabolizing genes in the susceptibility to the development of lung cancer using 110 primary lung cancer patients and 119 matched smoker controls. Together with data from the present study on DNA repair genes, we did not observe significant associations between any single variant genotype for several DNA-repair and chemical-metabolizing genes (XPD...
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