Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Aug 1999

Butkiewicz D, Cole K J, Phillips D H, Harris C C, Chorazy M

Abstract excerpt

The CYP and GST genetic polymorphisms, controlling metabolism of xenobiotics, are considered to influence an individual's susceptibility to environmental and occupational carcinogens and predisposition to cancer. In the study, the effect of the GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms was investigated in relation to PAH-DNA adduct levels in non-tumourous lung tissue from non-small cell lung cancer (NSCLC)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 CYP1A1
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to DNA Adducts

Share to Environmental Pollutants

Share to Glutathione Transferase

Share to Poland

Share to Smoking

Source

Identifiers

PMID: 10493307
DOI: 10.1097/00008469-199908000-00008

Genes

GSTM1
GSTP1
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels.PMID 10493307Read ↗

Glutathione S-transferase M1 and P1 metabolic polymorphism and lung cancer predisposition.Semantic proximity Read ↗

Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study.Semantic proximity Read ↗

Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk.Semantic proximity Read ↗

Molecular epidemiological study of non-small-cell lung cancer from an environmentally polluted region of Poland.Semantic proximity Read ↗

Human Lung Carcinogen--DNA Adduct Levels Mediated by Genetic Polymorphisms In VivoSemantic proximity Read ↗

CYP1A1 and GSTM1 polymorphisms and lung cancer risk in Chinese populations: a meta-analysis.Semantic proximity Read ↗

Comparison of DNA adduct levels in nasal mucosa, lymphocytes and bronchial mucosa of cigarette smokers and interaction with metabolic gene polymorphisms.Semantic proximity Read ↗

[Effects of CYP1A1 and GSTM1 gene polymorphisms and BPDE-DNA adducts on lung cancer].Semantic proximity Read ↗

DNA adduct level in lung tissue may act as a risk biomarker of lung cancer.Semantic proximity Read ↗

Association between GSTM1 polymorphism and DNA adduct concentration in the occupational workers exposed to PAHs: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk.Semantic proximity Read ↗

Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.