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Article

Effect of XPD/ERCC2 polymorphisms on chromosome aberration frequencies in smokers and on sensitivity to the mutagenic tobacco-specific nitrosamine NNK.

Environmental and molecular mutagenesis - 1 Jan 2004

Affatato Alessandra A, Wolfe Kevin J, Lopez Mirtha S, Hallberg Csilla, Ammenheuser Marinel M, Abdel-Rahman Sherif Z

Abstract excerpt

Polymorphisms in DNA-repair genes could contribute to the interindividual differences in cancer susceptibility in smokers. By reducing DNA-repair capacity, these polymorphisms may influence the net level of smoking-induced genetic damage significantly, a critical step in the cascade of events leading to cancer. In this biomonitoring study, we examined the relationship between polymorphisms in the DNA-repair gene...

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Source

Identifiers

PMID: 15199548
DOI: 10.1002/em.20032

Genes

ERCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of XPD/ERCC2 polymorphisms on chromosome aberration frequencies in smokers and on sensitivity to the mutagenic tobacco-specific nitrosamine NNK.PMID 15199548Read ↗

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