Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of NOD2 variants in spondylarthritis.

Arthritis and rheumatism - 1 Jun 2002

Crane Alison M, Bradbury Linda, van Heel David A, McGovern Dermot P B, Brophy Sinead, Rubin Laurence, Siminovitch Katherine A, Wordsworth B Paul, Calin Andrei, Brown Matthew A

Abstract excerpt

OBJECTIVE: To investigate the role of the gene NOD2 in susceptibility to, and clinical manifestations of, ankylosing spondylitis (AS). METHODS: A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Intracellular Signaling Peptides and Proteins

Share to Lod Score

Share to Nod2 Signaling Adaptor Protein

Share to Proteins

Share to Spondylarthritis

Source

Identifiers

PMID: 12115195
DOI: 10.1002/art.10329

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of NOD2 variants in spondylarthritis.PMID 12115195Read ↗

Inflammatory bowel disease genetics: Nod2.Semantic proximity Read ↗

Significant role of genetics in IBD: the NOD2 gene.Semantic proximity Read ↗

The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations.Semantic proximity Read ↗

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations.Semantic proximity Read ↗

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.Semantic proximity Read ↗

The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.Semantic proximity Read ↗

A Novel Rare Missense Variation of the <em>NOD2</em> Gene: Evidences of Implication in Crohn’s DiseaseSemantic proximity Read ↗

NOD2 Polymorphisms May Direct a Crohn Disease Phenotype in Patients With Very Early-Onset Inflammatory Bowel Disease.Semantic proximity Read ↗

NOD2 in Crohn's Disease-Unfinished Business.Semantic proximity Read ↗

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease.Semantic proximity Read ↗

Cellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohn's disease.Semantic proximity Read ↗

The Nod2 Gene in Crohn's Disease: Implications for Future Research Into the Genetics and Immunology of Crohn's DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.