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Article

NOD2 in Crohn's Disease-Unfinished Business.

Journal of Crohn's & colitis - 3 Apr 2023

Ashton James J, Seaby Eleanor G, Beattie R Mark, Ennis Sarah

Abstract excerpt

Studies of Crohn's disease have consistently implicated NOD2 as the most important gene in disease pathogenesis since first being identified in 2001. Thereafter, genome-wide association, next-generation sequencing and functional analyses have all confirmed a key role for NOD2, but despite this, NOD2 also has significant unresolved complexity. More recent studies have reinvigorated an early hypothesis that NOD2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36006803
DOI: 10.1093/ecco-jcc/jjac124
PMCID: PMC10069614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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