Article
Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus.
Disease models & mechanisms - 1 Sept 2014
Crampton Steve P, Morawski Peter A, Bolland Silvia
Abstract excerpt
Systemic lupus erythematosus (SLE) represents a challenging autoimmune disease from a clinical perspective because of its varied forms of presentation. Although broad-spectrum steroids remain the standard treatment for SLE, they have many side effects and only provide temporary relief from the symptoms of the disease. Thus, gaining a deeper understanding of the genetic traits and biological pathways that confer...
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