Article
Genetics of SLE in mice.
Springer seminars in immunopathology - 1 Oct 2006
Kono Dwight H, Theofilopoulos Argyrios N
Abstract excerpt
Genetic studies in spontaneous, induced, and gene-manipulated mouse models of SLE have provided significant insights into the potential number and diversity of genes that can promote, resist, and modify lupus susceptibility. Novel genes and mechanisms of disease pathogenesis have also been identified. Importantly, mouse models have provided an initial view of the genomic landscape of lupus-affecting genes, and...
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