Article
The effect of location and direction of an episomal gene on the restoration of a phenotype by functional complementation in Leishmania.
Molecular and biochemical parasitology - 1 Jul 2002
Pedrosa André L, Cruz Angela K
Abstract excerpt
The feasibility of genetic manipulation in trypanosomatids has allowed the introduction of molecular approaches for the investigation of gene function. The development of cosmids that carry approximately 40 kb of insert and can be easily introduced in trypanosomatids greatly increased the possibility of gene rescue by functional complementation in these parasites. Although functional complementation is widely...
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