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Recent advances in Leishmania reverse genetics: Manipulating a manipulative parasite

17 Jun 2017

Abstract excerpt

In this review we describe the expanding repertoire of molecular tools with which to study gene function in Leishmania. Specifically we review the tools available for studying functions of essential genes, such as plasmid shuffle and DiCre, as well as the rapidly expanding portfolio of available CRISPR/Cas9 approaches for large scale gene knockout and endogenous tagging. We include detail on approaches that allow...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 28629934
DOI: 10.1016/j.molbiopara.2017.06.005

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