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Article

Genetic complementation in apicomplexan parasites.

Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002

Striepen Boris, White Michael W, Li Catherine, Guerini Michael N, Malik S-Banoo, Logsdon John M, Liu Chang, Abrahamsen Mitchell S

Abstract excerpt

A robust forward genetic model for Apicomplexa could greatly enhance functional analysis of genes in these important protozoan pathogens. We have developed and successfully tested a genetic complementation strategy based on genomic insertion in Toxoplasma gondii. Adapting recombination cloning to genomic DNA, we show that complementing sequences can be shuttled between parasite genome and bacterial plasmid,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11959921
DOI: 10.1073/pnas.092525699
PMCID: PMC122944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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