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Article

Cardiovascular phenotypes of kinin B2 receptor- and tissue kallikrein-deficient mice.

Hypertension (Dallas, Tex. : 1979) - 1 Jul 2002

Trabold Fabien, Pons Sandrine, Hagege Albert A, Bloch-Faure May, Alhenc-Gelas François, Giudicelli Jean-François, Richer-Giudicelli Christine, Meneton Pierre

Abstract excerpt

To clarify the role of the kallikrein-kinin system in cardiovascular homeostasis, the systemic and regional hemodynamics of kinin B2 receptor-deficient (B2-/-) and tissue kallikrein-deficient (TK-/-) mice were compared with their wild-type (WT) littermates on a pure C57BL/6 genetic background. B2-/-, TK-/-, and WT adult mice were normotensive and displayed normal hemodynamic (left ventricular [LV] pressure,...

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Identifiers

PMID: 12105144
DOI: 10.1161/01.hyp.0000021747.43346.95

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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