Article
Dilated and failing cardiomyopathy in bradykinin B(2) receptor knockout mice.
Circulation - 7 Dec 1999
Emanueli C, Maestri R, Corradi D, Marchione R, Minasi A, Tozzi M G, Salis M B, Straino S, Capogrossi M C, Olivetti G, Madeddu P
Abstract excerpt
BACKGROUND: The activation of B(2) receptors by kinins could exert cardioprotective effects in myocardial ischemia and heart failure. METHODS AND RESULTS: To test whether the absence of bradykinin B(2) receptors may affect cardiac structure and function, we examined the developmental changes in b...
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