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Article

Apolipoprotein E genotype and cognitive impairment in community-dwelling black older adults.

International journal of psychiatry in medicine - 1 Jan 2002

Harwood Dylan G, Barker Warren W, Ownby Raymond L, Mullan Michael, Duara Ranjan

Abstract excerpt

OBJECTIVE: The relationship between the epsilon 4 allele of the apolipoprotein E gene (APOE-epsilon4) located on chromosome 19 and Alzheimer's disease is well documented among Caucasian populations. However, the findings of research addressing the link between APOE polymorphism and neurocognitive functioning in populations of African origin from around the world have been equivocal. Therefore, the current study...

Topics

Aged
Apolipoproteins E
Black People
Catchment Area, Health
Cognition Disorders
Female
Florida
Gene Frequency
Genotype
Humans
Male
Neuropsychological Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Residence Characteristics

Severity of Illness Index

Black or African American

Source

Identifiers

PMID: 12075916
DOI: 10.2190/1W2E-190C-RG27-VHUJ

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12075916-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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