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Article

Apolipoprotein e genotype, cortisol, and cognitive function in community-dwelling older adults.

The American journal of psychiatry - 1 Nov 2008

Lee Brian K, Glass Thomas A, Wand Gary S, McAtee Matthew J, Bandeen-Roche Karen, Bolla Karen I, Schwartz Brian S

Abstract excerpt

BACKGROUND: Elevated cortisol indicates stress and may be a risk factor for cognitive decline in aging. Genetic factors may influence individual vulnerability to the adverse effects of stress on cognitive function in aging. METHOD: The authors investigated whether the gene-environment interaction between the genotype for the apolipoprotein E gene (APOE) and cortisol predicted cognitive performance in older urban...

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Identifiers

PMID: 18593777
DOI: 10.1176/appi.ajp.2008.07091532
PMCID: PMC2579316

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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