The APOE epsilon4 allele is associated with decline on delayed recall performance in community-dwelling older adults.

doi:10.1111/j.1532-5415.1998.tb01532.x

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Article

The APOE epsilon4 allele is associated with decline on delayed recall performance in community-dwelling older adults.

Journal of the American Geriatrics Society - 1 Dec 1998

O'Hara R, Yesavage J A, Kraemer H C, Mauricio M, Friedman L F, Murphy G M

Abstract excerpt

OBJECTIVE: This study investigated whether the Apolipoprotein (APOE) epsilon4 allele was associated with cognitive decline in community-dwelling older adults. DESIGN: Longitudinal cognitive performance of older adults with the epsilon3/epsilon4 genotype was compared with that of older adults with the epsilon3/epsilon3 genotype. SETTING: Aging Clinical Research Center, Stanford University. PARTICIPANTS: One...

Topics

Adult
Aged
Aged, 80 and over
Alzheimer Disease
Apolipoprotein E3
Apolipoprotein E4
Apolipoproteins E
Dementia
Female
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Longitudinal Studies

Male

Mental Recall

Neuropsychological Tests

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 9848808
DOI: 10.1111/j.1532-5415.1998.tb01532.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9848808-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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