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Article

Racial differences in the influence of the APOE epsilon 4 allele on cognitive decline in a sample of community-dwelling older adults.

Gerontology - 1 Jan 2009

Sawyer Kathryn, Sachs-Ericsson Natalie, Preacher Kristopher J, Blazer Dan G

Abstract excerpt

BACKGROUND: Most, but not all, past studies have suggested that the APOE genotype is a risk factor for dementia in whites but not African Americans. This paper first describes explanations as to why some studies may have failed to detect the effect of APOE genotype in African American samples. Briefly, studies have been limited by various methodological problems including small sample sizes, dichotomous measures...

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Source

Identifiers

PMID: 18525196
DOI: 10.1159/000137666

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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