Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling elderly sample.

doi:10.1097/00002093-200201000-00002

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Article

Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling elderly sample.

Alzheimer disease and associated disorders - 1 Jan 2000

Harwood Dylan G, Barker Warren W, Ownby Raymond L, Mullan Michael, Duara Ranjan

Abstract excerpt

The epsilon 4 (epsilon 4) and epsilon 2 (epsilon 2) alleles of the apolipoprotein gene (APOE) located on chromosome 19 have been associated with increased and decreased risk for Alzheimer disease (AD) in older adults, respectively. However, there is a dearth of studies examining the relation of APOE polymorphism with cognitive functioning among community-dwelling ethnic minority elderly. This study examined the...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoprotein E2
Apolipoprotein E4
Apolipoproteins E
Cognition Disorders
Female
Florida
Genetic Carrier Screening

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetics, Population

Hispanic or Latino

Humans

Male

Mental Status Schedule

Middle Aged

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 11882744
DOI: 10.1097/00002093-200201000-00002

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11882744-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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