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Article

Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway.

Molecular biology of the cell - 1 Feb 2004

Dalal Seema, Rosser Meredith F N, Cyr Douglas M, Hanson Phyllis I

Abstract excerpt

NSF and p97 are related AAA proteins implicated in membrane trafficking and organelle biogenesis. p97 is also involved in pathways that lead to ubiquitin-dependent proteolysis, including ER-associated degradation (ERAD). In this study, we have used dominant interfering ATP-hydrolysis deficient mutants (NSF(E329Q) and p97(E578Q)) to compare the function of these AAA proteins in the secretory pathway of mammalian...

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Identifiers

PMID: 14617820
DOI: 10.1091/mbc.e03-02-0097
PMCID: PMC329284

Genes

NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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