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Article

NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex.

Neuron - 28 Mar 2002

Hanley Jonathan G, Khatri Latika, Hanson Phyllis I, Ziff Edward B

Abstract excerpt

AMPA receptor (AMPAR) trafficking is crucial for synaptic plasticity that may be important for learning and memory. NSF and PICK1 bind the AMPAR GluR2 subunit and are involved in trafficking of AMPARs. Here, we show that GluR2, PICK1, NSF, and alpha-/beta-SNAPs form a complex in the presence of ATPgammaS. Similar to SNARE complex disassembly, NSF ATPase activity disrupts PICK1-GluR2 interactions in this complex....

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Source

Identifiers

PMID: 11931741
DOI: 10.1016/s0896-6273(02)00638-4

Genes

NSF
PICK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex.PMID 11931741Read ↗

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